SCALE-UP (Student-Centered Active Learning Environment for Undergraduate Programs) shares state-of-the-art learning studios, teaching methods, and instructional materials that are based on more than a decade of discipline-based education research. The overarching goal of this project is to develop and assess an interactive, hands-on environment that seamlessly integrates classroom and laboratory instruction, producing stimulating and effective instruction for all students. The instructional methodology includes active and cooperative learning techniques and is founded on the premise that actively engaged students stand a better chance to discover and understand science principles, be fascinated by science phenomena, and be better prepared to succeed in their career of choice.